diff --git a/sci-libs/onnxruntime/Manifest b/sci-libs/onnxruntime/Manifest
index 9570730864..4941c0a95a 100644
--- a/sci-libs/onnxruntime/Manifest
+++ b/sci-libs/onnxruntime/Manifest
@@ -1,2 +1,3 @@
 DIST eigen-3.4.0_p20250216.tar.bz2 2272941 BLAKE2B c86764a5c31b978d09f9f8f458a982fb16c2cdfd053e0c7a371fbe5b9c64bead42c25fb7d4cb795eb5ee7ff1800bb51fac6783ad0881dd69dee5d463ccd213e3 SHA512 3c9fab41bde1ee4b8f5ba21c991a75cc73e104cdb48f3377b5fc51afae8cbb5e891c39e4fd998c5263178a8962b09d9d907b9d125dfddc50bc2ec5171917d6b8
 DIST onnxruntime-1.24.3.tar.gz 283631211 BLAKE2B 14de894e0d69fb51679186756bf2d0cbb8e5429f7553866d8aedebdc0fabae76fd7ea5f95c9da8b449a7411dc6d91a5974717a98f67cf445ef893285f7614c95 SHA512 1c4108d0a2cbcbbc24186914f954751afdac347c36a3a97b95b3daf0c9cf4b98d07d1fde4dfbc37a107acbdd658f88eff310c22fe8dd73266c6a9a7817af3c49
+DIST onnxruntime-1.24.4.tar.gz 283642312 BLAKE2B f6d964c73fb1e5ad92643473b8e5ebede824cf558714600d3a99a105d282e2374f8b22f13ed506f13dad553c55ed099e8dca7899301c8a1737a21e55e4fcb890 SHA512 53b3aed02e085c83aa3c7e1faffeae7f70675d6770bc44d148085ded47940f29471eef76e0c4565bbb471f0f814610e0d1892ce9305c63d011fe851a22b1f7ab
diff --git a/sci-libs/onnxruntime/onnxruntime-1.24.4.ebuild b/sci-libs/onnxruntime/onnxruntime-1.24.4.ebuild
new file mode 100644
index 0000000000..48979af06d
--- /dev/null
+++ b/sci-libs/onnxruntime/onnxruntime-1.24.4.ebuild
@@ -0,0 +1,147 @@
+# Copyright 1999-2026 Gentoo Authors
+# Distributed under the terms of the GNU General Public License v2
+
+EAPI=8
+
+PYTHON_COMPAT=( python3_{12..13} )
+
+inherit cmake edo flag-o-matic python-r1
+
+EIGEN_COMMIT="1d8b82b0740839c0de7f1242a3585e3390ff5f33"
+
+DESCRIPTION="Cross-platform, high performance ML inferencing and training accelerator"
+HOMEPAGE="
+	https://onnxruntime.ai
+	https://github.com/microsoft/onnxruntime
+"
+SRC_URI="
+	https://github.com/microsoft/onnxruntime/archive/refs/tags/v${PV}.tar.gz -> ${P}.tar.gz
+	https://gitlab.com/libeigen/eigen/-/archive/${EIGEN_COMMIT}/eigen-${EIGEN_COMMIT}.tar.bz2 ->
+		eigen-3.4.0_p20250216.tar.bz2
+"
+
+LICENSE="MIT"
+SLOT="0"
+KEYWORDS="~amd64"
+IUSE="python test"
+REQUIRED_USE="${PYTHON_REQUIRED_USE}"
+RESTRICT="!test? ( test )"
+
+RDEPEND="
+	dev-cpp/abseil-cpp:=
+	dev-libs/cpuinfo
+	dev-libs/protobuf:=
+	dev-libs/re2:=
+	sci-ml/onnx[disableStaticReg]
+
+	python? (
+		${PYTHON_DEPS}
+		dev-python/coloredlogs[${PYTHON_USEDEP}]
+		dev-python/flatbuffers[${PYTHON_USEDEP}]
+		>=dev-python/numpy-2[${PYTHON_USEDEP}]
+		dev-python/packaging[${PYTHON_USEDEP}]
+		dev-python/protobuf[${PYTHON_USEDEP}]
+		dev-python/sympy[${PYTHON_USEDEP}]
+	)
+"
+DEPEND="
+	${RDEPEND}
+	dev-cpp/ms-gsl
+	dev-cpp/nlohmann_json
+	dev-cpp/safeint
+	dev-libs/boost
+	dev-libs/date
+	dev-libs/flatbuffers
+
+	python? (
+		dev-python/pybind11[${PYTHON_USEDEP}]
+		sci-libs/dlpack
+	)
+"
+BDEPEND="
+	${PYTHON_DEPS}
+
+	test? (
+		dev-cpp/gtest
+
+		python? ( dev-python/pytest[${PYTHON_USEDEP}] )
+	)
+"
+
+PATCHES=(
+	"${FILESDIR}/${PN}-1.22.2-relax-the-dependency-on-flatbuffers.patch"
+	"${FILESDIR}/${PN}-1.24.3-use-system-libraries.patch"
+)
+
+CMAKE_USE_DIR="${S}/cmake"
+
+src_configure() {
+	# Python is used at build time unconditionally
+	python_setup
+
+	local mycmakeargs=(
+		-Donnxruntime_BUILD_SHARED_LIB=on
+
+		-Donnxruntime_BUILD_UNIT_TESTS=$(usex test)
+		-Donnxruntime_ENABLE_PYTHON=$(usex python)
+
+		# This is required until a newer version of Eigen3 comes out
+		-DFETCHCONTENT_SOURCE_DIR_EIGEN3="${WORKDIR}/eigen-${EIGEN_COMMIT}"
+
+		# This makes it possible for `find_path` to find the `onnx-ml.proto` file
+		-DCMAKE_INCLUDE_PATH="$(python_get_sitedir)"
+
+		-Wno-dev
+	)
+
+	append-ldflags -Wl,-z,noexecstack
+	cmake_src_configure
+}
+
+# Adapted from `run_onnxruntime_tests` in `tools/ci_build/build.py`
+python_test() {
+	cd "${S}/cmake_build" || die
+	epytest --pyargs \
+		onnxruntime_test_python.py \
+		onnxruntime_test_python_backend.py \
+		onnxruntime_test_python_mlops.py \
+		onnxruntime_test_python_sparse_matmul.py
+}
+
+src_test() {
+	local -x GTEST_FILTER="*:-ActivationOpNoInfTest.Softsign:LayoutTransformationPotentiallyAddedOpsTests.OpsHaveLatestVersions"
+	cmake_src_test
+
+	if use python ; then
+		python_test
+	fi
+}
+
+# There is some custom logic in `setup.py`
+python_install() {
+	cd "${S}/cmake_build" || die
+	edo "${EPYTHON}" ../setup.py install \
+		--prefix="${EPREFIX}/usr" \
+		--root="${D}"
+
+	local libs=(
+		"libonnxruntime.so.${PV}"
+		"libonnxruntime_providers_shared.so"
+	)
+	for lib in "${libs[@]}"; do
+		ln -fsr "${ED}/usr/$(get_libdir)/${lib}" "${D}/$(python_get_sitedir)/onnxruntime/capi/${lib}" || die
+	done
+
+	rm -rf "${D}/$(python_get_sitedir)"/*.egg-info || die
+	python_optimize
+}
+
+src_install() {
+	cmake_src_install
+
+	if use python ; then
+		python_foreach_impl python_install
+	fi
+
+	dodoc "${S}/"{README.md,LICENSE}
+}